despite 可以放句首嗎？

Can 'despite' Be Placed at the Beginning of a Sentence?

Since 'despite' is a preposition, it must be followed by a noun or a gerund. It can appear either at the beginning or in the middle of a sentence. If you want to include a clause, you should use the structure 'despite the fact that.' Keep in mind that this usage tends to sound more formal. For instance, Despite the lack of sleep, Annie was still energetic.